“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone.  Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor.  Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”

Mineralys is a fully remote company.

Senior Director, Global Marketing

Reporting to the CCO, the Senior Director, Global Marketing will lead the development and execution of the ex-U.S. commercial strategy. This individual will play a critical role in shaping global market strategy, ensuring alignment with U.S. commercial objectives, and optimizing long-term global revenue potential.

This role requires a highly strategic and analytical leader who can operate cross-functionally across commercial, clinical, regulatory, and business development to define market entry strategies, influence development programs, and secure partnerships across key international markets.

Key Responsibilities:

Global Commercial Strategy (Ex-U.S.)

• Lead global (ex-U.S.) market identification, prioritization, and segmentation across key geographies
• Develop and execute go-to-market strategies tailored by geography and indication
• Define optimal pathways to market entry, including indication prioritization

Cross-Functional Leadership

• Partner closely with Clinical and Regulatory teams to shape development programs that align with commercial objectives and regulatory requirements
• Influence clinical study design and sequencing to maximize global commercial opportunity
• Ensure alignment across stakeholders to maintain a unified strategy
• Partner with Market Access to evaluate pricing and reimbursement dynamics across international markets, including health technology assessment (HTA) environments
• Identify and mitigate risks related to international reference pricing and Most Favored Nation (MFN) implications

Business Development & Partnerships

• Lead business development efforts to identify, evaluate, and secure strategic partners for market entry
• Structure and support partnership models (e.g., licensing, co-promotion, regional partnerships)
• Manage partner strategy to ensure successful execution in priority markets

Strategic Analytics & Decision-Making

• Conduct rigorous market assessments, including epidemiology, competitive landscape, and access dynamics
• Develop commercial forecasts and scenario analyses to inform prioritization and investment decisions
• Provide strategic recommendations to senior leadership based on data-driven insights

Required Experience:

• 10+ years of biopharmaceutical commercial experience, including global or ex-U.S. marketing
• Demonstrated success in multi-market strategy development and execution
• Strong experience in chronic disease markets; cardiovascular experience preferred.
• Proven ability to collaborate with clinical and regulatory teams to shape development programs
• Experience in early-stage or pre-market environments (Phase II or earlier strongly preferred)
• Track record of business development and partnership execution

Capabilities & Skills

• Exceptional analytical and strategic thinking skills, particularly in market access and pricing dynamics
• Deep understanding of global reimbursement systems and HTA bodies (e.g., Europe, Japan)
• Strong ability to navigate complex trade-offs between global and U.S. commercial strategies
• Excellent cross-functional leadership and influence skills
• Ability to operate effectively in a fast-paced, emerging biotech environment

Travel

• This position requires up to 20% travel.  Frequently travel is outside the local area and overnight. 

These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.

US Salary Range:  $250,000 - $265,000

#LI-REMOTE