Senior/Executive Director, Endometrial Cancer Brand Lead

USA (Unknown)

$270K/yr – $315K/yrSenior Level12+ years expFull time

Posted 2 months ago

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Job Summary

Own the US EC brand and launch readiness at scale while shaping biomarker-driven strategy, access considerations, and field execution across the patient journey.

  • Brand and Launch Ownership: map a multi-year roadmap, set KPIs, and align cross-functional plans with franchise and corporate priorities.
  • Strategic Messaging and Evidence: translate clinical data into differentiated, compliant claims and communications for key oncology stakeholders.
  • Cross-Functional Governance: lead launch governance, field readiness, and cross-team execution spanning Sales, Medical, Access/HEOR, Analytics, Regulatory, and Compliance.

Job Description

Responsibilities

  • Own the U.S. EC brand strategy and multi-year commercial roadmap; deliver an annual Brand Plan/AOP with clear objectives, KPIs, milestones, and investment choices aligned to franchise and corporate priorities.
  • Define and evolve positioning, message platform, and customer value proposition; translate clinical and real-world evidence into differentiated, compliant claims and communications.
  • Lead lifecycle planning and strategic scenario work (e.g., competitive response, biomarker-driven opportunities, combination strategies, line-of-therapy expansion opportunities, and treatment sequencing dynamics), partnering with cross-functional leaders to evaluate options and trade-offs.
  • Lead biomarker strategy in partnership with Medical Affairs, Market Access, Diagnostics/External Partners, and Field teams, with attention to tumor testing workflows, education needs, and barriers to patient identification.
  • Drive U.S. EC launch strategy and readiness from pivotal data readout through launch execution, defining launch milestones, critical path, and cross-functional workstreams including positioning, messaging, field readiness, access readiness, omnichannel activation, and patient support.
  • Lead the U.S. EC Launch Team and governance cadence, driving timely decisions, risk and issue escalation, and integrated execution across Sales, Medical, Market Access/HEOR, Analytics, Regulatory, Legal/Compliance, and Commercial Operations to ensure an on-time, high-quality launch.
  • Develop customer segmentation and targeting strategy across key stakeholders, including gynecologic oncologists, medical oncologists, academic cancer centers, community oncology practices, integrated delivery networks, and key accounts.
  • Translate strategy into customer engagement plans, field execution priorities, promotional programs, and pull-through tools.
  • Serve as senior marketing lead to Sales leadership and the field organization; ensure tight alignment on priorities, messaging, execution standards, and feedback loops.
  • Maintain accountability for brand performance versus plan; establish operating rhythms and dashboards to monitor demand, share, customer engagement, and execution quality.
Karyopharm Therapeutics logo

Karyopharm Therapeutics

3.9 Glassdoor

Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company whose dedication to pioneering novel cancer therapies is fueled by a belief in the extraordinary strength and courage of patients with cancer. As an organization, Karyopharm is on a mission to improve lives and defeat cancer. In its role as leaders in XPO1 inhibition, Karyopharm delivers on its mission by creating a focused pipeline that targets multiple high unmet need cancer indications, including multiple myeloma, endometrial cancer,myelofibrosis, and diffuse large B-cell lymphoma (DLBCL).

Founded in 2008
Newton Centre, Massachusetts, USA
312 employees (6 in marketing)
77% recommend to a friend
89% CEO approval

Traffic Signals

Monthly Visitors
8.9K
Traffic Source Mix
Search
38.5%
Direct
44.4%
Referral
6.4%
Social
9.3%
Paid
1.3%

Headcount Trend

Current headcount: ~312

Marketing Team

Marketing Team Size
6 (2% of company)

Funding

Total Funding
$637.2M
Last Raise
$30M
Post IPO Equity, 3 months ago

Funding History

  • Mar 2026
    Post IPO Equity • $30M
  • Oct 2025
    Post IPO Equity • $33M
  • Oct 2025
    Post IPO Debt • $27.5M

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